Sr Scientist, Clinical Pharmacology

Overview

• Contribute to the development of innovative RNAi therapeutics in a hybrid work environment.
• Support clinical pharmacology efforts, including PK/PD analysis and modeling for drug development projects.
• Collaborate with multidisciplinary teams to ensure comprehensive pharmacokinetic and pharmacodynamic data integration.
• Provide scientific expertise for regulatory submissions and clinical study protocols.
• Engage in cutting-edge research to advance RNAi therapeutic applications.
• Maintain knowledge of current literature and trends in clinical pharmacology and pharmacometric modeling.
• Leverage advanced analytical tools to visualize and interpret PK/PD data effectively.
• Participate in a dynamic and innovative team environment focused on excellence.

Key Responsibilities & Duties

• Lead pharmacokinetic and pharmacodynamic data analysis, interpretation, and reporting for clinical projects.
• Conduct noncompartmental analysis and PK/PD modeling to support drug development decisions.
• Prepare and contribute to regulatory documents, including IND, CTA, and NDA submissions.
• Collaborate with cross-functional teams, including research, bioanalytical, and clinical development groups.
• Develop and execute clinical study protocols and analyze resulting data.
• Utilize advanced software tools for pharmacokinetic modeling and data visualization.
• Stay updated on advancements in pharmacology and modeling techniques.
• Contribute to the strategic planning and execution of clinical pharmacology initiatives.

Job Requirements

• Ph.D. in Pharmacokinetics, Pharmacology, or related field with 2+ years of industry experience.
• Proficiency in pharmacokinetics, PK/PD modeling, ADME principles, and clinical data interpretation.
• Hands-on experience with Phoenix WinNonlin, R, NONMEM, or similar modeling software.
• Strong verbal and written communication skills for effective collaboration and presentations.
• Ability to work in a hybrid environment and collaborate with cross-functional teams.
• Knowledge of regulatory submission processes and clinical study protocol development.
• Commitment to continuous learning and application of pharmacometric principles.
• Eligibility for relocation and sponsorship as required.