Scientist IV

Duties:

· Design/develop/perform various functional genomics assays, such as CRISPR pool screening, bulk RNA-seq, single cell–seq, spatial transcriptomics, CITE-seq, WES, Perturb-seq and 10X Multiome on tissue, cell or nuclei suspensions;

· Assist with technical guidance and training, as appropriate, to Research scientists a) in FGSL technologies and techniques and b) to conduct assays, troubleshoot and solve technical issues;

· Serve as scientific monitor for assay performance and project management at external CROs;

· Documents and maintains detailed laboratory records in accordance with SOP's and policies;

· Operates and maintains lab equipment in collaboration with other lab members;

· Assists with budget preparation and acquisition of necessary supplies and equipment;

· Defines and performs appropriate QC measures;

· Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field;

· Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation;

· Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports

· Automate processing and results reporting and delivery;

· Reports and treats data with a high level of integrity and ethics.

Requirements:

· Demonstrated experience with CRISPR assays · Demonstrated experience with next-generation sequencing (NGS) and functional genomics, single cell technologies; · Proficient in cell culture.

· Experience in automation and software programing is a plus; · Able to perform variety of FGS experimental techniques at the same time; · Demonstrated experience working in a multi-disciplinary and collaborative environment; · Ability to troubleshoot FGS experiments both individually and as part of a team.

· Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner.

·Ph.D. or Master's degree from an accredited institution with 6+ years of experience in molecular, cell biology, or related scientific discipline.

· Cell Culture