06Jun

Almost a century ago the comic strip hero Popeye popularized spinach, attributing his amazing strength to the leafy green. Within a few short years of Popeye’s first appearance in 1929, spinach sales soared.

Now, spinach has a new claim to fame. Biologists are using microscopic parts of the plant to speed up photosynthesis, the process of using light to convert carbon dioxide into energy and oxygen.

Still limited to laboratory research, the implications of the research, published this month in Science, are profound. The faster process — up to 100 times faster — could be harnessed to manufacture drugs, accelerate the growth of crops and even help fight climate change.

Tobias Erb, a synthetic biologist at the Max Planck Institute for Terrestrial Microbiology and a lead researcher on the project, said his team expects to be able to modify the output of their photosynthesis process to produce different types of organic compounds, including drugs.

By engineering the new photosynthesis into agricultural crops, they could go from seedling to harvest in far less time, enabling farmers to produce more food than is now possible.

One particularly intriguing possibility is to use this new, faster photosynthesis process to help fight climate change by enabling plants to absorb up to 10 times more carbon dioxide than they do naturally.

“Artificial trees, that’s a cool idea,” Erb told the online magazine Inverse.

Erb and the research team caution that much work remains before the process can be scaled – right now the artificial structure degrades after just a few hours.

“In the natural system there are automatic repair systems,” Chemical & Engineering News quotes Erb as saying. “In our system that is not possible yet.”

Nevertheless, bioscientists not involved with the research, see it as a major step forward.

“It’s a profound discovery,” says Paul King, a physical biochemist at the National Renewable Energy Laboratory in Golden, Colorado.

Declaring it “very ambitious,” Frances Arnold, professor of chemical engineering, bioengineering and biochemistry at the California Institute of Technology, predicted the work will improve current efforts to convert carbon dioxide directly into useful chemicals.

Photo by Louis Hansel @shotsoflouis on Unsplash

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Jun 6, 2023

What’s the Difference Between the COVID Vaccines?

With the approval last month of the Moderna vaccine by the Food and Drug Administration, we now have two COVID-19 vaccines available. Two more – one from Johnson & Johnson the other from AstraZeneca – are on the way and could be approved as soon as February.

Healthcare workers, residents of nursing facilities and some first responders have already received the Pfizer vaccine, the first one approved by the FDA. Moderna has begun shipping its vaccine with the first of the 25 million initial doses administered last month.

People eager to be immunized have inundated doctors’ offices and clinics asking when the vaccine will be available. The best answer is soon.

Which one, though, will you receive? And does it make any difference?

The answer to the first question is whichever vaccine can be obtained the quickest or, in some cases, whichever your health plan recommends. It really doesn’t make any difference to you.

Both vaccines require two separate doses to reach maximum effectiveness 21 days apart for Pfizer and 28 days for the Moderna version. Both protect about equally well. The FDA data shows Pfizer is 95% effective after both doses. Moderna is 94.1%.

Unlike most other vaccines, these two vaccines use pieces of protein from the SARS-CoV-2 virus to prompt the body to create antibodies. Conventional vaccines, like the annual flu shot, are manufactured from viruses typically grown in chicken eggs. These chicken grown viruses are then killed or weakened to become vaccines.

The COVID vaccines employ messenger RNA (mRNA), a newer technology. These vaccines “teach” the body to replicate the little bit of the CoV-2 protein, which, in turn, creates an immune response causing the body to make the antibodies that provide the protection against the virus.

The most significant difference between the Moderna and the Pfizer vaccines is how they must be stored. Both can survive for a few days in standard refrigeration. For longer periods, the less stable Pfizer vaccine must be kept in ultra-low temperatures below -94 F. That makes shipping and storing Pfizer’s vaccine somewhat more complicated, especially outside urban areas where the low temperature refrigeration is not easily available.

“At the end of the day, these two vaccines are pretty similar,” Dr. Thomas Russo, professor and chief of infectious disease at the State University of New York, tells Health. “Grab it while you can.”

Photo by Hakan Nural

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