06Jun

As Big Pharma and the entire pharmaceutical sector generally transforms (see our previous articles), so too is the way consumers buy their drugs and fill prescriptions.

For the first time since grocers set-up pharmacies inside their markets, the number of these grocery pharmacies is

declining. The Wall Street Journal says hundreds of regional markets “are closing or selling pharmacy counters, which have been struggling as consumers make fewer trips to fill prescriptions and big drugstore chains tighten their grip on the U.S. market.”

Consolidation has concentrated market share in CVS and Walgreens, which together accounted for more than 40% of all prescription revenue in 2018. Together, the two operate more than 20,000 retail locations. In 2015, CVS acquired 1,672 in store pharmacies from Target. Last year, Walgreens broadened its partnership with the giant Kroger grocery chain spurring speculation it could buy the grocer’s 2,270 in-store pharmacies.

Consumer’s have also changed how they fill prescriptions, switching to mail order and buying in larger quantities, less often.

The Journal explained that smaller grocers don’t have the clout to negotiate higher reimbursement rates from insurers, nor do they have the amenities like nationwide networks and walk-in clinics that the largest chains do. Their pharmacies tend to operate at or below break-even, but served as a customer convenience.

“There is the benefit of having a pharmacy relative to the grocery-sale lift and the convenience factor of having both in the store, but the economics do not work,” Raley’s CEO Keith Knopf told The Journal.

With the closing of these grocery pharmacies comes the loss of jobs. Reporting on the update of the Department of Labor’s Occupational Outlook Handbook last fall, Drug Channels said jobs for pharmacists is projected to be flat through 2028. But jobs for retail pharmacists will decline by 11,000. Hospitals, outpatient care centers and home healthcare agencies will add pharmacist jobs as will mail order services.

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Jun 6, 2023

What’s the Difference Between the COVID Vaccines?

With the approval last month of the Moderna vaccine by the Food and Drug Administration, we now have two COVID-19 vaccines available. Two more – one from Johnson & Johnson the other from AstraZeneca – are on the way and could be approved as soon as February.

Healthcare workers, residents of nursing facilities and some first responders have already received the Pfizer vaccine, the first one approved by the FDA. Moderna has begun shipping its vaccine with the first of the 25 million initial doses administered last month.

People eager to be immunized have inundated doctors’ offices and clinics asking when the vaccine will be available. The best answer is soon.

Which one, though, will you receive? And does it make any difference?

The answer to the first question is whichever vaccine can be obtained the quickest or, in some cases, whichever your health plan recommends. It really doesn’t make any difference to you.

Both vaccines require two separate doses to reach maximum effectiveness 21 days apart for Pfizer and 28 days for the Moderna version. Both protect about equally well. The FDA data shows Pfizer is 95% effective after both doses. Moderna is 94.1%.

Unlike most other vaccines, these two vaccines use pieces of protein from the SARS-CoV-2 virus to prompt the body to create antibodies. Conventional vaccines, like the annual flu shot, are manufactured from viruses typically grown in chicken eggs. These chicken grown viruses are then killed or weakened to become vaccines.

The COVID vaccines employ messenger RNA (mRNA), a newer technology. These vaccines “teach” the body to replicate the little bit of the CoV-2 protein, which, in turn, creates an immune response causing the body to make the antibodies that provide the protection against the virus.

The most significant difference between the Moderna and the Pfizer vaccines is how they must be stored. Both can survive for a few days in standard refrigeration. For longer periods, the less stable Pfizer vaccine must be kept in ultra-low temperatures below -94 F. That makes shipping and storing Pfizer’s vaccine somewhat more complicated, especially outside urban areas where the low temperature refrigeration is not easily available.

“At the end of the day, these two vaccines are pretty similar,” Dr. Thomas Russo, professor and chief of infectious disease at the State University of New York, tells Health. “Grab it while you can.”

Photo by Hakan Nural

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